Can I use desktop 24 hours a day?

Hello!
I'm just wondering if I can use my desktop 24 hours a day without shutting down? I have an online job which requires me to use my computer almost 24 hours a day 5 days a week.
Is there any risk if I use it 14 to 24 hours a day? If yes, please let me know what are those risk. I'm just afraid that my computer won't work anymore if I use it almost 24 hours a day. I'll be waiting for your comments/solutions. Thanks.
Jasmine
