Cannot start or quit the Office program

Hi,
When I attempt to start or quit the Office program error message appears with NET Framework Core CLR Hotfix Package. Is this problem with emulation Ethernet driver or anything else? If you have any clue please suggest me soon. Any help would be appreciated. I am a user of Win 7 64bit OS. Thanks.

Attachmate.Emulation.Frame.exe-Fatal Error
CLR Error: 80004005.
The program will now terminate.
