Can I Use Linspire to Run Windows Applications?

Hi,
I've been using Linspire as my primary operating system and I love the way it is better than Windows. However, I just can't seem to run and install Windows applications.
I heard that Linspire is in-tie with Windows so I'm expecting it can run Windows applications. Are there configurations or installation methods I've missed? Can I run Windows applications flawlessly in Linspire?
