Antivirus has deleted all the files

I have an external hard disk. I used to take my system backup into the external hard disk. For some reasons, my friend took the hard disk and after returning I scanned the hard disk with Microsoft essential security antivirus.
I found that the hard disk is virus corrupted. I quarantine the virus and found that all data was gone but in the properties of the hard disk it shows the exact size of the hard disk.
Now I wonder where the data has gone.
Do I need to run some data recovery software in the hard disk.
Please assist me in this case.
Thanks in advance.
