Is it safe to delete thumbs.dp file?

I am seeing a series of thumbs.dp file on my Windows XP especially if I am on the thumbnail view.
Some of it, although it takes up small disk space,
I still want to delete a series of it which will sum to maybe 500kb or more. I only have 60GB on my hard disk, and I will need to free some space. Is it safe to delete it?
If so, how can I totally delete all of it? Please help.
