Task Manager itself is Not Responding in Windows 8?

Currently I have Windows 8 pre-installed(Factory Installed) and while working on my laptop when is not hung up and when I press Ctrl+Alt+Del, Task Manager appears in not-responding state. I need to kill some non-responding processes, but Task Manager itself doesn't Respond. What should I do?
Laptop: Sony Vaio SVP1321WSNB VAIO Pro 13.
Windows is Genuine.
