Exchange 2010 Troubleshooting – Out of Office reply issue

At any time they tried to switch on or off my outlook the Out of Office respond saying your automatic reply settings cannot be displayed because the server is currently unavailable. Try again later. The error message you can see below too. Please help in resolving this issue. I am new to outlook usage.

Microsoft Outlook
Your automatic reply settings cannot be displayed the server is currently unavailable. Try again later.
OK
