Retail Man error #- 121

Dear all,
This problem I don’t know how to fix and I really need help. This situation is similar even if I want to save PDF or any other format and even if I want to send invoice I got the same error message. On my computer OS is Windows Vista. Please help
Thank you in advance
Noreen
Warning
C:tempSI22.pdf could not be created due to error#-121
