Is it safe to delete .ini files in my desktop?

Hi,
First of all, I am not the only user of our desktop. So I cannot really say if there was a change in the configuration settings of our computer. But as for me, I did not change any thing.
Our desktop is operating on Windows Vista. The issue is that, I am seeing desktop.ini files on the desktop. I am afraid to delete it thinking that I may not be able to boot it again or I might ruin our computer. So as of the moment, I didn't do anything on it. What I want to know is how to get rid of it?
Please help me.
