Error The system cannot find the file specified

I think I have done something terribly wrong and now I am not able to get a software application up and running.
I had an infection on my machine and I had to run a, Antivirus and an Anti Spyware program to clean the same. In the cleaning process it has removed one of my software application’s file.
When I try to open the application it comes up with the following error message
SimpleErrors Sample Application
The system cannot find the file specified.
I don’t know how to proceed further with this error message. Can anyone help me with this issue?
