Disk cannot be read from or written to when syncing iPod

Hello Brainy,
Friends I am new to this kind of operation so kindly bear with me. When I try to copy some songs from the disk, I ended up with an error message. I am not sure whether I can do this or iTunes is compatible with this operations. I tried several times but nothing worked out. Please guide me with some suggestions. Thanks a lot.

Attempting to copy to the disk iPod failed. The disk could not be read from or written to.
