The Application Virtualization Client could not launch the application

The Application Virtualization Client could not launch the application

Actually, there are different errors related to “application virtualization error” that can appear when using App-V but unfortunately I think you are the only one that received the error code “461758B-0B211304-00000C15” when using the program. This is really or they consider it as a problem in the design which puts it as a bug.

There are even other users experiencing this error when opening Adobe Reader or simply opening a PDF file and there is really no clear solution to this. If your search points you to access and add something to the environment variables in Windows, here’s how you can access it. Right-click on My Computer and select Properties. Go to Advanced tab and click Environment Variables located at the bottom of the window. See image.

On the next screen you will see two sections, the “User variables for [username]” above and the “System variables” below. See image.

The “System variables” are the variables used by the operating system or by Windows. None of these variables must be removed or else the system might become unstable. The “User variables” located above are your personal variables or the variables added by the programs you install. So I think if you need to add a variable or two, this is the section to place it.